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A two-stage chromogenic assay which measures unfractionated heparin in human plasma by measurement of Factor IIa (thrombin) activity. The inhibitory effect of antithrombin III (ATIII) on Factor IIa (thrombin), Factor Xa and other coagulation serine proteases in plasma is increased several-thousand fold by heparin. This inhibition accounts for the anticoagulant effect of heparin. In the first stage, heparin in the patient sample is allowed to react with ATIII. In the second stage, the heparin–ATIII complex formed inhibits the added thrombin. The residual thrombin hydrolyzes the thrombin-specifi
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Company:
Date:
December 16, 2008
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Measures heparin Cofactor II (dermatan sulphate cofactor) in human plasma. The assay is a three stage chromogenic assay using Dermatan Sulfate and excess thrombin. In the first stage, Dermatan sulphate is added to the diluted sample. In the second stage, thrombin is added and inhibition of the thrombin activity occurs. In the third stage, the residual thrombin activity is measured using the thrombin specific chromogenic substrate SPECTROZYME® TH. The heparin Cofactor II concentration is inversely proportional to the residual thrombin concentration.
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Company:
Date:
December 16, 2008
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Functional clotting assay with
unparalleled specificity and
sensitivity
Not influenced by:
Lupus anticoagulants, FVIII,
Protein C or S, Heparins,
AT, Fibrinogen, abnormal
conditions of PT, FX, TFPI and
D‑Dimer
Cost savings due to PCR-like
sensitivity:
Complete discrimination
between homozygous,
heterozygous and normal
Reduced need for PCR
Faster turnaround time
Validated protocols for major
coagulation analyzers available
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Company:
Date:
December 16, 2008
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Quantitative Plasma-based Factor XIII Assay Combo Pack
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Company:
Date:
December 16, 2008
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The only functional plasma-based assay for coagulation factor XIII activity, Pefakit Factor XIII exhibits improved
specificity and sensitivity compared to other tests. With a wide measurement range, it can detect
severe deficiencies as well as increased levels of factor XIII and it exhibits no interference from heparin, ammonia,
fibrinogen or a-antiplasmin. The kit is available in a microtiter plate format and includes all reagents
for a single run. A multi-run combination pack is also available.
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Company:
Date:
December 16, 2008
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Rapid and automated
quantification of thrombin
formation
Easy to use:
Short turnaround time
Fast determination of
thrombin formation
kinetics
Two step assay
Simple analysis algorithm
Protocols for major
routine analyzers
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Company:
Date:
December 16, 2008
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Pefakit PiCT Danaparoid Calibrators
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Company:
Date:
December 16, 2008
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Plasma based
functional assay for
the determination of
Reptilase® Time
Superior method for
characterization of
dysfibrinogenemias
Insensitive to heparin
Easy to use:
Simple one-step test
Short turnaround time
Clotting assay
Suitable for manual
procedures, fibrometers
and automated systems
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Company:
Date:
December 16, 2008
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Functional assay based on
direct substrate cleavage
Specific for TAFI
Adaptable to coagulation
analyzers and MTP
Easy to use:
Fast turnaround time
Stable reagents
Calibrators and
controls available
Validated protocols for
major routine analyzers
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Company:
Date:
December 16, 2008
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The VisuLize™ FVIII Antigen kit is an Enzyme Immunoassay for the quantitative determination of Factor VIII antigen in human plasma samples
and Factor VIII concentrates using the double antibody enzyme linked immuno-sorbent assay (ELISA).
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Company:
Date:
August 19, 2010
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