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Iron exists in serum complexed with transferrin, a transport protein. Most
early procedures for iron determination involved dissociation of the iron from
the iron-protein complex, precipitation of the proteins, and then measurement
of the iron content of the protein free filtrate.
Many chromagens have been used in the determination including
thiocyanate o-phenanthroline, bathophenanthroline and TPTZ. In 1971,
Persijn et al.1 presented a method using the chromagen ferrozine, described
by Stookey.2 This method did not require protein precipitation and was more
sensitive than previous methods. Th
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Company:
Date:
December 10, 2008
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Iron & TIBC
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Company:
Date:
December 10, 2008
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Iron (for TC-Matrix)
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Company:
Date:
December 10, 2008
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Iron in serum exists primarily as a complex with transferrin. Each transferrin molecule binds two atoms of ferric-iron. This mechanism serves for transport of iron from mucosal cells to the body's storage areas such as the liver and bone marrow. Elevated serum iron utilization (lead poisoning), accelerated release of iron from body stores (neocrotic hepatitis), defective iron storage (pernicious anemia) and increased iron absorption (hemochromatosis). Decreased serum iron is found with dietary deficiency, nephrosis, and increased body demand (pregnancy). Clinical interpretation of abnormally l
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Company:
Date:
December 10, 2008
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Liquid-stable, ready-to-use reagent
Ferene method
Linearity up to 1000 µg/dL
Wavelength 600 nm, Hg 595 nm
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Company:
Date:
December 10, 2008
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Liquid-stable, ready-to-use reagent
Ferene method
Linearity up to 1000 µg/dL
Wavelength 600 nm, Hg 595 nm
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Company:
Date:
December 10, 2008
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Liquid-stable, ready-to-use reagent
Ferene method
Linearity up to 1000 µg/dL
Wavelength 600 nm, Hg 595 nm
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Company:
Date:
December 10, 2008
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Liquid-stable, ready-to-use reagent
Ferene method
Linearity up to 1000 µg/dL
Wavelength 600 nm, Hg 595 nm
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Company:
Date:
December 10, 2008
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Liquid-stable, ready-to-use reagent
Ferene method
Linearity up to 1000 µg/dL
Wavelength 600 nm, Hg 595 nm
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Company:
Date:
December 10, 2008
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The Iron-Binding Capacity (IBC) test (also known as Total Iron-Binding Capacity (TIBC) test) is used to determine the total ability of serum to combine with excess ferric ions. The iron-binding protein in serum is known as siderophilin or transferrin, and normally is only partially filled with iron (in the form of ferric ions). The IBC test measures the total amount of iron which transferrin is capable of binding.
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Company:
Date:
December 10, 2008
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