|
Laboratory Corporation of America
|
|
|
|
ST and ALT (SGPT) are increased in Reye syndrome.1,2 In infectious mononucleosis, LD (LDH) is commonly considerably higher than AST. Trauma (including head trauma and including surgery) and other striated muscle diseases, including dystrophy, dermatomyositis, trichinosis, polymyositis, and gangrene cause AST increases. Both AST and ALT elevations are found with Duchenne muscular dystrophy. Look for high CK in myositis, high LD5 (or isomorphic pattern in some instances of polymyositis) on LD isoenzymes.
In myocardial infarction AST peaks about 24 hours after infarct and returns to normal 3-7
|