|
|
Atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP) are members of a family of
hormones secreted from the atrium, ventricle, and vascular endothelial cells. Three receptors, type A (specific for ANP and BNP),
type B (specific for CNP and ANP) and the clearance receptor, have been characterised.
The mature form of BNP, secreted predominantly by the cardiac ventricle, is formed from a high molecular weight precursor,
proBNP (1-108).
BNP is stored in the human cardiac tissue mainly as BNP-32, with a lesser amount of the precursor peptide, proBNP
|