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Bladder cancer is the most common tumor of the urinary system and the fifth most common cancer in North America. It is estimated that 75,000 new cases of bladder cancer will be diagnosed in 2008, and that 16,000 individuals will die from it. The World Health Organization estimates that there are 330,000 new cases annually worldwide. Bladder cancer prevalence is steadily increasing and its projected rise is 28 by 2010 for both men and women.
The diagnosis of bladder cancer currently relies on identifying malignant cells by urine cytology, with or without adjunct tests, and also by visualizing
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