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Angiotensin II is a primary reactive vasoconstrictor, the main stimulus for aldosterone release,
and one of the causative factors of chronic hypertension. The active angiotensin II octapeptide
is released via a tightly controlled series of prohormones and proteases as diagrammed below.
Normal human plasma angiotensin II levels are from 10-30 pg/ml when measured at rest in the
supine position; they increase on standing, exercise, dehydration, or sodium depletion. The
unique, patented 'Immobilized Antigen' technology of this angiotensin II immunometric assay
allows reliable detection of 1-2 pg/m
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